Composition

0.25 g: Each vial contains Ceftiofur Sodium USP sterile powder equivalent to 0.25 g Ceftiofur.

0.5 g: Each vial contains Ceftiofur Sodium USP sterile powder equivalent to 0.5 g Ceftiofur.

1 g: Each vial contains Ceftiofur Sodium USP sterile powder equivalent to 1 g Ceftiofur

Pharmacology

Ceftiofur is a broad spectrum third generation Cephalosporin and beta-lactam antibiotic that is resistant to the action of beta-lactamase. It is active against both gram-positive and gram-negative bacteria. The additional benefit of Ceftiofur is that its metabolite, desfuroylceftiofur has also antimicrobial activity. It kills bacteria by inhibiting the synthesis of bacterial cell wall.

Indications

Livestock

Tifur Vet is indicated for the treatment of bovine respiratory diseases (shipping fever, pneumonia) associated with Mannheimia haemolytica, Pasteurella multocida & Histophilus somni, acute bovine interdigital necrobacillosis (foot rot, pododermatitis) associated with Fusobacterium necrophorum & Bacteroides melaninogenicus and genital tract infections (endometritis, postpuerperial metritis, toxic puerperal metritis, pyometra) associated with E. coli, Fusobacterium necrophorum, Arcanobacterium pyogenes.

Poultry

Tifur Vet is indicated for the control of early chick mortality associated with E. coli in day-old chicks and day-old turkey poults.

Dosage & Administration

Route of administration: For intramuscular/ subcutaneous injection only.

Reconstitution

0.25 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 5 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.

0.5 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 10 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.

1 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 20 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.

Cattle/Sheep/Goat: 1.1-2.2 mg/kg body weight (1 ml/23-45 kg) by IM injection once daily for 3-5 days.

Dog: 2.2 mg/kg body weight (1 ml/23 kg) by SC injection once daily for 5-14 days. 

Horse: 2.2-4.4 mg/kg body weight (1 ml/12-23 kg) by IM injection once daily & continued for 2 days after disappearing of clinical signs.

Swine: 3-5 mg/kg body weight by IM injection once daily for 3 consecutive days.

Day-Old Chicks: 0.08-0.2 mg/chick by SC injection. 1 ml (50 mg/ml) reconstituted solution will be required for the treatment of approximately 250 to 625 day-old chicks.

Day-Old Turkey Poults: 0.17-0.5 mg/poult by SC injection in the neck region. 1 ml (50 mg/ml) reconstituted solution will be required for the treatment of approximately 100 to 294 day-old turkey poults.

Or as directed by the registered Veterinary Physician.